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science
Jun 05, 2020
Sleep deprivation in flies and mice leads to increased ROS (Reactive oxygen species) molecules in the gut. This is shown to be highly correalted to lethality. To show the causality, the over-expression of anti-oxiodants restores normal lifespan in the animals.
alexandra vaccaro
allan rechtschaffen
animals
biology
carol everson
dogs
dragana rogulja
fruit flies
giorgio gilestro
guts
harvard medical school
inflammation
john allan hobson
keishi nambara
maria mikhailovna manaseina
metabolism
neuroscience
paul shaw
physiology
rats
reactive oxygen species
ros
ruth benca
sleep
sleep deprivation
university of chicago
yosef kaplan dor
science
Apr 01, 2019
Shape-Shifting Mitochondria Direct Stem Cells’ Fate
biology
developmental biology
cell biology
cells
metabolism
eukaryotes
organelles
biochemistry
molecular biology
mitochondria
adenosine triphosphate
atp
shape-shifting
powerhouse
fusion
fission
university of ottawa
neurons
dynamics
apoptosis
programmed cell death
cytochrome c
navdeep chandel
northwestern university
university of chicago
reactive oxygen species
ros
peroxides
singlet oxygen
hydroxyl radicals
proteins
blood
fat
stem cells
glycolysis
cytoplasm
oxidative phosphorylation
differentiation
mireille khacho
self-renewal
cell fate
clifford folmes
mayo clinic
neurogenesis
alessandro prigione
max delbrück center for molecular medicine
ruth slack
neurodevelopmental disorders
autism
neurodegenerative diseases
alzheimer’s disease
amyotrophic lateral sclerosis
als
mice
humans
david chan
california institute of technology
signaling
metabolites
luca scorrano
university of padua
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