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Jul 06, 2020

Toxic metallic air pollution nanoparticles are getting inside the crucial, energy-producing structures within the hearts of people living in polluted cities, causing cardiac stress. The study underlines the need for governments across the world to tackle ultrafine particulate pollution

biology cardiology cell biology ecology/environment environmental health molecular biology pollution/remediation toxicology

science

Apr 23, 2020

New study reveals life's earliest evolution was more complicated than previously suspected.

bacteriology biology biotechnology cell biology evolution genetics molecular biology technology/engineering/computer science

science

Apr 03, 2020

POssible coronavirus drug identified by Australian scientists

medicine/health microbiology molecular biology public health

science

Mar 17, 2020

Scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease. Dubbed 'CHyMErA', for Cas Hybrid for Multiplexed Editing and Screening Applications, the method can be applied to any type of mammalian cell.

biochemistry bioinformatics biology biomedical/environmental/chemical engineering biotechnology cell biology genes genetics molecular biology

science

Mar 14, 2020

Researchers have discovered that the enzyme SPRK1 leads the first step in untangling a sperm's genome, kicking out special packing proteins, which opens up the paternal DNA and allows for major reorganization in a matter of hours. The study was published in "Cell".

cell biology developmental/reproductive biology fertility medicine/health molecular biology

science

Mar 13, 2020

Scientists have described the structure of an endogenously sourced, functioning neuronal amyloid at atomic resolution. It is composed of self-aggregated Orb2, the fruit fly version of the mRNA-binding cytoplasmic polyadenylation element-binding (CPEB) protein, which is linked to long-term memory.

biochemistry biology cell biology genetics molecular biology

science

Feb 12, 2020

Research has found people who vape exhibit similar chemical modifications in their overall genome and in parts of their DNA as people who smoke cigarettes. This is the first study to show that vapers, like smokers, have these biologically important changes detectable in their blood cells.

addiction biochemistry biology cancer genes genetics medicine/health molecular biology smoking/tobacco

science

Feb 09, 2020

Discovery paves path forward in the fight against the deadliest form of malaria

biology genes infectious/emerging diseases medicine/health microbiology molecular biology parasitology

science

Jan 30, 2020

New research presents a first-of-its-kind cancer treatment strategy that targets a pro-tumor protein FROUNT and suppresses tumor-associated macrophages. Through animal experiments, the researchers found that by regulating FROUNT expression in TAMs, cancer growth could be suppressed.

biochemistry biology cancer cell biology clinical trials genetics immunology/allergies/asthma medicine/health molecular biology

science

Dec 11, 2019

Potentially toxic chemicals from LCDs in nearly half of household dust samples tested. Researchers are sounding the alarm about liquid crystal monomers--the chemical building blocks of everything from flat screen TVs to solar panels--and the potential threat they pose to humans and the environment.

biology ecology/environment environmental health gastroenterology hardware molecular biology public health toxicology

science

Nov 25, 2019

Intestinal stem cell genes may link dietary fat and colon cancer

cancer cell biology gastroenterology genes genetics medicine/health molecular biology nutrition/nutrients

science

Nov 14, 2019

Extinct giant ape directly linked to the living orangutan: Researchers have succeeded in reconstructing the evolutionary relationship between a 2-million-year-old giant primate and the living orangutan

archaeology biology evolution genetics molecular biology paleontology

science

Jul 21, 2019

New research identifies gene, DUX4, that hides cancer cells from immunotherapy. Over expression of DUX4 is also the cause of genetic disease, Facioscapulohumeral Muscular Dystrophy (FSHD). Finding a way to inhibit DUX4 would benefit early detection and more for cancer but could also eliminates FSHD.

biology cancer cell biology developmental/reproductive biology genetics health care microbiology molecular biology

science

May 27, 2019

Scientists uncover a trove of genes that could hold key to how humans evolved.Dozens of genes previously thought to have similar roles across species are in fact unique to humans. These genes code for a class of proteins known as transcription factors, or TFs, which control gene activity.

bioinformatics biology genes genetics molecular biology

science

May 27, 2019

New link found between viral infection and Alzheimer’s disease: In animal models of Alzheimer's disease, mice developed the disease within 48 hours of HSV-1 infection in the brain. In absence of an HSV-1 infection the process normally takes several months.

alzheimer's disease biology immunology/allergies/asthma molecular biology virology

science

Apr 11, 2019

JUUL electronic cigarette products linked to cellular damage. The nicotine concentrations are sufficiently high to be cytotoxic, or toxic to living cells, when tested in vitro with cultured respiratory system cells

addiction cell biology medicine/health mental health molecular biology public health smoking/tobacco toxicology

science

Apr 01, 2019

Shape-Shifting Mitochondria Direct Stem Cells’ Fate

biology developmental biology cell biology cells metabolism eukaryotes organelles biochemistry molecular biology mitochondria adenosine triphosphate atp shape-shifting powerhouse fusion fission university of ottawa neurons dynamics apoptosis programmed cell death cytochrome c navdeep chandel northwestern university university of chicago reactive oxygen species ros peroxides singlet oxygen hydroxyl radicals proteins blood fat stem cells glycolysis cytoplasm oxidative phosphorylation differentiation mireille khacho self-renewal cell fate clifford folmes mayo clinic neurogenesis alessandro prigione max delbrück center for molecular medicine ruth slack neurodevelopmental disorders autism neurodegenerative diseases alzheimer’s disease amyotrophic lateral sclerosis als mice humans david chan california institute of technology signaling metabolites luca scorrano university of padua

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